A formal procedure for the probabilistic design assessment of a composite structure is described. The uncertainties in all aspects of a composite structure (constituent material properties, fabrication variables, structural geometry, service environments, etc.), which result in the uncertain behavior in the composite structural responses, are included in the assessment. The probabilistic assessment consists of design criteria, modeling of composite structures and uncertainties, simulation methods, and the decision making process. A sample case is presented to illustrate the formal procedure and to demonstrate that composite structural designs can be probabilistically assessed with accuracy and efficiency.